Differential integrity of TALE nuclease genes following adenoviral and lentiviral vector gene transfer into human cells

The array of genome editing strategies based on targeted double-stranded DNA break formation have recently been enriched through the introduction of transcription activator-like type III effector (TALE) nucleases (TALENs). To advance the testing of TALE-based approaches, it will be crucial to delive...

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Bibliographic Details
Main Authors: Holkers, Maarten, Maggio, Ignazio, Liu, Jin, Janssen, Josephine M., Miselli, Francesca, Mussolino, Claudio, Recchia, Alessandra, Cathomen, Toni, Gonçalves, Manuel A. F. V.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2013
Subjects:
Methods Online
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597656/
https://ncbi.nlm.nih.gov/pubmed/23275534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks1446
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