Analysis of Hepatitis C Virus Decline during Treatment with the Protease Inhibitor Danoprevir Using a Multiscale Model

The current paradigm for studying hepatitis C virus (HCV) dynamics in patients utilizes a standard viral dynamic model that keeps track of uninfected (target) cells, infected cells, and virus. The model does not account for the dynamics of intracellular viral replication, which is the major target o...

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Bibliografiske detaljer
Main Authors: Rong, Libin, Guedj, Jeremie, Dahari, Harel, Coffield, Daniel J., Levi, Micha, Smith, Patrick, Perelson, Alan S.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597560/
https://ncbi.nlm.nih.gov/pubmed/23516348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002959
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