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Analysis of Hepatitis C Virus Decline during Treatment with the Protease Inhibitor Danoprevir Using a Multiscale Model

The current paradigm for studying hepatitis C virus (HCV) dynamics in patients utilizes a standard viral dynamic model that keeps track of uninfected (target) cells, infected cells, and virus. The model does not account for the dynamics of intracellular viral replication, which is the major target o...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Rong, Libin, Guedj, Jeremie, Dahari, Harel, Coffield, Daniel J., Levi, Micha, Smith, Patrick, Perelson, Alan S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597560/
https://ncbi.nlm.nih.gov/pubmed/23516348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002959
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