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Analysis of Hepatitis C Virus Decline during Treatment with the Protease Inhibitor Danoprevir Using a Multiscale Model

The current paradigm for studying hepatitis C virus (HCV) dynamics in patients utilizes a standard viral dynamic model that keeps track of uninfected (target) cells, infected cells, and virus. The model does not account for the dynamics of intracellular viral replication, which is the major target o...

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Detalhes bibliográficos
Main Authors: Rong, Libin, Guedj, Jeremie, Dahari, Harel, Coffield, Daniel J., Levi, Micha, Smith, Patrick, Perelson, Alan S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597560/
https://ncbi.nlm.nih.gov/pubmed/23516348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002959
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