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Localized Lipid Packing of Transmembrane Domains Impedes Integrin Clustering
Integrin clustering plays a pivotal role in a host of cell functions. Hetero-dimeric integrin adhesion receptors regulate cell migration, survival, and differentiation by communicating signals bidirectionally across the plasma membrane. Thus far, crystallographic structures of integrin components ar...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3597534/ https://ncbi.nlm.nih.gov/pubmed/23516344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002948 |
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