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Lipid packing drives the segregation of transmembrane helices into disordered lipid domains in model membranes

Cell membranes are comprised of multicomponent lipid and protein mixtures that exhibit a complex partitioning behavior. Regions of structural and compositional heterogeneity play a major role in the sorting and self-assembly of proteins, and their clustering into higher-order oligomers. Here, we use...

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Autori principali: Schäfer, Lars V., de Jong, Djurre H., Holt, Andrea, Rzepiela, Andrzej J., de Vries, Alex H., Poolman, Bert, Killian, J. Antoinette, Marrink, Siewert J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3029762/
https://ncbi.nlm.nih.gov/pubmed/21205902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1009362108
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