Epstein - Barr Virus Transforming Protein LMP-1 Alters B Cells Gene Expression by Promoting Accumulation of the Oncoprotein ΔNp73α

Many studies have proved that oncogenic viruses develop redundant mechanisms to alter the functions of the tumor suppressor p53. Here we show that Epstein-Barr virus (EBV), via the oncoprotein LMP-1, induces the expression of ΔNp73α, a strong antagonist of p53. This phenomenon is mediated by the LMP...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Accardi, Rosita, Fathallah, Ikbal, Gruffat, Henri, Mariggiò, Giuseppe, Le Calvez-Kelm, Florence, Voegele, Catherine, Bartosch, Birke, Hernandez-Vargas, Hector, McKay, James, Sylla, Bakary S., Manet, Evelyne, Tommasino, Massimo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597522/
https://ncbi.nlm.nih.gov/pubmed/23516355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003186
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi