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Oncoprotein E7 from Beta Human Papillomavirus 38 Induces Formation of an Inhibitory Complex for a Subset of p53-Regulated Promoters

Our previous studies on cutaneous beta human papillomavirus 38 (HPV38) E6 and E7 oncoproteins highlighted a novel activity of IκB kinase beta (IKKβ) in the nucleus of human keratinocytes, where it phosphorylates and stabilizes ΔNp73α, an antagonist of p53/p73 functions. Here, we further characterize...

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Detalhes bibliográficos
Main Authors: Saidj, Djamel, Cros, Marie-Pierre, Hernandez-Vargas, Hector, Guarino, Francesca, Sylla, Bakary S., Tommasino, Massimo, Accardi, Rosita
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807916/
https://ncbi.nlm.nih.gov/pubmed/24006445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01047-13
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