Epstein-Barr Virus Down-Regulates Tumor Suppressor DOK1 Expression

The DOK1 tumor suppressor gene encodes an adapter protein that acts as a negative regulator of several signaling pathways. We have previously reported that DOK1 expression is up-regulated upon cellular stress, via the transcription factor E2F1, and down-regulated in a variety of human malignancies d...

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Bibliographic Details
Main Authors: Siouda, Maha, Frecha, Cecilia, Accardi, Rosita, Yue, Jiping, Cuenin, Cyrille, Gruffat, Henri, Manet, Evelyne, Herceg, Zdenko, Sylla, Bakary S., Tommasino, Massimo
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014463/
https://ncbi.nlm.nih.gov/pubmed/24809689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004125
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