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Functional Genomic Analysis of the let-7 Regulatory Network in Caenorhabditis elegans
The let-7 microRNA (miRNA) regulates cellular differentiation across many animal species. Loss of let-7 activity causes abnormal development in Caenorhabditis elegans and unchecked cellular proliferation in human cells, which contributes to tumorigenesis. These defects are due to improper expression...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3597506/ https://ncbi.nlm.nih.gov/pubmed/23516374 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003353 |
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