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Comprehensive discovery of endogenous Argonaute binding sites in Caenorhabditis elegans
MicroRNAs (miRNAs) regulate gene expression by guiding Argonaute proteins to specific target mRNA sequences. Identification of bona fide miRNA target sites in animals is made challenging by uncertainties regarding the base-pairing requirements between miRNA and target as well as the location of func...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2834287/ https://ncbi.nlm.nih.gov/pubmed/20062054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1745 |
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