Regional white matter hyperintensity volume, not hippocampal atrophy, predicts incident Alzheimer’s disease in the community

BACKGROUND: New onset Alzheimer’s disease (AD) is often attributed to degenerative changes in the hippocampus. However, the contribution of regionally distributed small vessel cerebrovascular disease, visualized as white matter hyperintensities (WMH) on MRI, remains unclear. OBJECTIVE: To determine...

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Bibliografische gegevens
Hoofdauteurs: Brickman, Adam M., Provenzano, Frank A., Muraskin, Jordan, Manly, Jennifer J., Blum, Sonja, Apa, Zoltan, Stern, Yaakov, Brown, Truman R., Luchsinger, José A., Mayeux, Richard
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597387/
https://ncbi.nlm.nih.gov/pubmed/22945686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archneurol.2012.1527
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