White matter hyperintensities and cognition: Testing the reserve hypothes

OBJECTIVE: White matter hyperintensities (WMH), visualized on T2-weighted MRI, are thought to reflect small-vessel vascular disease. Much like other markers of brain disease, the association between WMH and cognition is imperfect. The concept of reserve may account for this imperfect relationship. T...

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Bibliographic Details
Main Authors: Brickman, Adam M., Siedlecki, Karen L., Muraskin, Jordan, Manly, Jennifer J., Luchsinger, José A., Yeung, Lok-Kin, Brown, Truman R., DeCarli, Charles, Stern, Yaakov
Format: Artigo
Language:Inglês
Published: 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891625/
https://ncbi.nlm.nih.gov/pubmed/19926168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2009.10.013
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