Feedback-controlled bolus plus infusion (FC-B/I) method for quantitative drug assessment in living brain with PET

We have developed a feedback-controlled bolus plus infusion (FC-B/I) method for monitoring the interaction between positron emission tomography (PET) ligands and their specific target molecules with PET. The usefulness of the FC-B/I method was evaluated by the direct interaction between [(11)C]raclo...

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Bibliographische Detailangaben
Hauptverfasser: Ohba, Hiroyuki, Harada, Norihiro, Nishiyama, Shingo, Kakiuchi, Takeharu, Kimura, Yuichi, Tsukada, Hideo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2013
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597362/
https://ncbi.nlm.nih.gov/pubmed/22968323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2012.134
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