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Sensitive and early detection of mitochondrial dysfunction in the liver of NASH model mice by PET imaging with (18)F-BCPP-BF

BACKGROUND: Nonalcoholic fatty liver disease is a common disorder that progresses from simple fatty liver (steatosis) to nonalcoholic steatohepatitis (NASH). It is thought that mitochondrial dysfunction plays a critical role in the progression of NASH. In this study, we developed a non-invasive meth...

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Detalhes bibliográficos
Publicado no:EJNMMI Res
Main Authors: Sakai, Toshihiro, Ohba, Hiroyuki, Nishiyama, Shingo, Kakiuchi, Takeharu, Inoue, Osamu, Tsukada, Hideo
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6047947/
https://ncbi.nlm.nih.gov/pubmed/30014266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-018-0420-6
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