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Endosomal NADPH oxidase regulates c-Src activation following hypoxia/reoxygenation injury
c-Src has been shown to activate NF-κB (nuclear factor κB) following H/R (hypoxia/reoxygenation) by acting as a redox-dependent IκBα (inhibitory κB) tyrosine kinase. In the present study, we have investigated the redox-dependent mechanism of c-Src activation following H/R injury and found that ROS (...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3597079/ https://ncbi.nlm.nih.gov/pubmed/18397177 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20071534 |
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