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Endosomal NADPH oxidase regulates c-Src activation following hypoxia/reoxygenation injury

c-Src has been shown to activate NF-κB (nuclear factor κB) following H/R (hypoxia/reoxygenation) by acting as a redox-dependent IκBα (inhibitory κB) tyrosine kinase. In the present study, we have investigated the redox-dependent mechanism of c-Src activation following H/R injury and found that ROS (...

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Detalles Bibliográficos
Main Authors: Li, Qiang, Zhang, Yulong, Marden, Jennifer J., Banfi, Botond, Engelhardt, John F.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597079/
https://ncbi.nlm.nih.gov/pubmed/18397177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20071534
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