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NADPH oxidase modulates myocardial Akt, ERK1/2 activation, and angiogenesis after hypoxia-reoxygenation

Recent studies have demonstrated that reactive oxygen species (ROS) mediate myocardial ischemia-reperfusion (I/R) and angiogenesis via the mitogen-activated protein kinases and the serine-threonine kinase Akt/protein kinase B pathways. NADPH oxidases are major sources of ROS in endothelial cells and...

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Detalhes bibliográficos
Main Authors: Chen, Jian-Xiong, Zeng, Heng, Tuo, Qin-Hui, Yu, Heidi, Meyrick, Barbara, Aschner, Judy L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2383323/
https://ncbi.nlm.nih.gov/pubmed/17220182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01138.2006
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