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Overexpression of angiopoietin-2 impairs myocardial angiogenesis and exacerbates cardiac fibrosis in the diabetic db/db mouse model

The angiopoietins/Tie-2 system is essential for the maintenance of vascular integrity and angiogenesis. The functional role of angiopoietin-2 (Ang-2) in the regulation of angiogenesis is dependent on other growth factors such as VEGF and a given physiopathological conditions. This study investigates...

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Autori principali: Chen, Jian-Xiong, Zeng, Heng, Reese, Jeff, Aschner, Judy L., Meyrick, Barbara
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322731/
https://ncbi.nlm.nih.gov/pubmed/22180648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00866.2011
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