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Phosphoinositide-3-kinases p110α and p110β mediate S phase entry in astroglial cells in the marginal zone of rat neocortex

In cells cultured from neocortex of newborn rats, phosphoinositide-3-kinases of class I regulate the DNA synthesis in a subgroup of astroglial cells. We have studied the location of these cells as well as the kinase isoforms which facilitate the S phase entry. Using dominant negative (dn) isoforms a...

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Autors principals: Müller, Rabea, Fischer, Catharina, Wilmes, Thomas, Heimrich, Bernd, Distel, Vanessa, Klugbauer, Norbert, Meyer, Dieter K.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596864/
https://ncbi.nlm.nih.gov/pubmed/23504389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2013.00024
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