Effect of hydrogen sulphide-donating sildenafil (ACS6) on erectile function and oxidative stress in rabbit isolated corpus cavernosum and in hypertensive rats

OBJECTIVE: To study the effect of the H(2)S-donating derivative of sildenafil (ACS6) compared to sildenafil citrate and sodium hydrosulphide (NaHS) on relaxation, superoxide formation and NADPH oxidase and type 5 phosphodiesterase (PDE5) expression in isolated rabbit cavernosal tissue and smooth mus...

Full description

Saved in:
Bibliographic Details
Main Authors: Shukla, Nilima, Rossoni, Giuseppe, Hotston, Matthew, Sparatore, Anna, Del Soldato, Piero, Tazzari, Valerio, Persad, Raj, Angelini, Gianni D., Jeremy, Jamie Y.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596780/
https://ncbi.nlm.nih.gov/pubmed/19245441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1464-410X.2009.08415.x
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items