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ACS6, a Hydrogen sulfide-donating derivative of sildenafil, inhibits homocysteine-induced apoptosis by preservation of mitochondrial function
BACKGROUND: The hydrogen sulfide-releasing sildenafil, ACS6, has been demonstrated to inhibit superoxide formation through donating hydrogen sulfide (H(2)S). We have found that H(2)S antagonizes homocysteine-induced oxidative stress and neurotoxicity. The aim of the present study is to explore the p...
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| Main Authors: | , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
BioMed Central
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3231821/ https://ncbi.nlm.nih.gov/pubmed/22146536 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-9912-1-20 |
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