Effect of hydrogen sulphide-donating sildenafil (ACS6) on erectile function and oxidative stress in rabbit isolated corpus cavernosum and in hypertensive rats

OBJECTIVE: To study the effect of the H(2)S-donating derivative of sildenafil (ACS6) compared to sildenafil citrate and sodium hydrosulphide (NaHS) on relaxation, superoxide formation and NADPH oxidase and type 5 phosphodiesterase (PDE5) expression in isolated rabbit cavernosal tissue and smooth mus...

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Main Authors: Shukla, Nilima, Rossoni, Giuseppe, Hotston, Matthew, Sparatore, Anna, Del Soldato, Piero, Tazzari, Valerio, Persad, Raj, Angelini, Gianni D., Jeremy, Jamie Y.
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596780/
https://ncbi.nlm.nih.gov/pubmed/19245441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1464-410X.2009.08415.x
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