Suppression of ribosomal reinitiation at upstream open reading frames in amino acid-starved cells forms the basis for GCN4 translational control.

GCN4 encodes a transcriptional activator of amino acid-biosynthetic genes in Saccharomyces cerevisiae that is regulated at the translational level by upstream open reading frames (uORFs) in its mRNA leader. uORF4 (counting from the 5' end) is sufficient to repress GCN4 under nonstarvation conditions...

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Detaylı Bibliyografya

Yayımlandı:	Mol Cell Biol
Asıl Yazarlar:	Abastado, J P, Miller, P F, Jackson, B M, Hinnebusch, A G
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	Taylor & Francis 1991
Konular:	Research Article
Online Erişim:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359655/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1986242/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.1.486-496.1991
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