Suppression of ribosomal reinitiation at upstream open reading frames in amino acid-starved cells forms the basis for GCN4 translational control.

GCN4 encodes a transcriptional activator of amino acid-biosynthetic genes in Saccharomyces cerevisiae that is regulated at the translational level by upstream open reading frames (uORFs) in its mRNA leader. uORF4 (counting from the 5' end) is sufficient to repress GCN4 under nonstarvation condi...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Abastado, J P, Miller, P F, Jackson, B M, Hinnebusch, A G
Format: Artigo
Langue:Inglês
Publié: 1991
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC359655/
https://ncbi.nlm.nih.gov/pubmed/1986242
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires