Down syndrome and the molecular pathogenesis resulting from trisomy of human chromosome 21

Chromosome copy number aberrations, anueploidies, are common in the human population but generally lethal. However, trisomy of human chromosome 21 is compatible with life and people born with this form of aneuploidy manifest the features of Down syndrome, named after Langdon Down who was a 19(th) ce...

Full description

Saved in:
Bibliographic Details
Main Authors: Ruparelia, Aarti, Wiseman, Frances, Sheppard, Olivia, Tybulewicz, Victor L.J., Fisher, Elizabeth M.C.
Format: Artigo
Language:Inglês
Published: Editorial Department of Journal of Biomedical Research 2010
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596542/
https://ncbi.nlm.nih.gov/pubmed/23554618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1674-8301(10)60016-4
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items