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Tc1 mouse model of trisomy-21 dissociates properties of short- and long-term recognition memory

The present study examined memory function in Tc1 mice, a transchromosomic model of Down syndrome (DS). Tc1 mice demonstrated an unusual delay-dependent deficit in recognition memory. More specifically, Tc1 mice showed intact immediate (30 sec), impaired short-term (10-min) and intact long-term (24-...

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Detalhes bibliográficos
Publicado no:Neurobiol Learn Mem
Main Authors: Hall, Jessica H., Wiseman, Frances K., Fisher, Elizabeth M.C., Tybulewicz, Victor L.J., Harwood, John L., Good, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4898594/
https://ncbi.nlm.nih.gov/pubmed/26868479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nlm.2016.02.002
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