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Down syndrome and the molecular pathogenesis resulting from trisomy of human chromosome 21

Chromosome copy number aberrations, anueploidies, are common in the human population but generally lethal. However, trisomy of human chromosome 21 is compatible with life and people born with this form of aneuploidy manifest the features of Down syndrome, named after Langdon Down who was a 19(th) ce...

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Autors principals: Ruparelia, Aarti, Wiseman, Frances, Sheppard, Olivia, Tybulewicz, Victor L.J., Fisher, Elizabeth M.C.
Format: Artigo
Idioma:Inglês
Publicat: Editorial Department of Journal of Biomedical Research 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596542/
https://ncbi.nlm.nih.gov/pubmed/23554618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1674-8301(10)60016-4
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