טוען...
Treatment of Arthritis by Macrophage Depletion and Immunomodulation: Testing an Apoptosis-Mediated Therapy in a Humanized Death Receptor Mouse Model
OBJECTIVE: To determine the therapeutic efficacy and immunomodulatory effect of an anti-human death receptor 5 (DR5) antibody, TRA-8, in eliminating macrophage subsets in a collagen II-induced arthritis (CIA) mouse model. METHODS: A chimeric human/mouse (hu/mo) DR5 transgenic (Tg) mouse, under the r...
שמור ב:
| Main Authors: | , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2011
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3596268/ https://ncbi.nlm.nih.gov/pubmed/22006294 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.33423 |
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