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Death Receptor 5—Targeted Depletion of Interleukin-23—Producing Macrophages, Th17, and Th1/17 Associated With Defective Tyrosine Phosphatase in Mice and Patients with Rheumatoid Arthritis
OBJECTIVE. Bidirectional interactions between granulocyte-macrophage colony-stimulating factor–positive (GM-CSF(+)) T cell and interferon regulatory factor 5–positive (IRF-5(+)) macrophages play a major role in autoimmunity. In the absence of SH2 domain-containing phosphatase 1 (SHP-1), GM-CSF–stimu...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3993980/ https://ncbi.nlm.nih.gov/pubmed/23818173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38057 |
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