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Death Receptor 5—Targeted Depletion of Interleukin-23—Producing Macrophages, Th17, and Th1/17 Associated With Defective Tyrosine Phosphatase in Mice and Patients with Rheumatoid Arthritis

OBJECTIVE. Bidirectional interactions between granulocyte-macrophage colony-stimulating factor–positive (GM-CSF(+)) T cell and interferon regulatory factor 5–positive (IRF-5(+)) macrophages play a major role in autoimmunity. In the absence of SH2 domain-containing phosphatase 1 (SHP-1), GM-CSF–stimu...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Li, Jun, Yang, PingAr, Wu, Qi, Li, Hao, Ding, Yana, Hsu, Hui-Chen, Spalding, David M., Mountz, John D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993980/
https://ncbi.nlm.nih.gov/pubmed/23818173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38057
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