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The tyrosine phosphatase SHP-1 dampens murine Th17 development

Th17 cells represent a subset of CD4(+) T helper cells that secrete the proinflammatory cytokine IL-17. Th17 cells have been ascribed both a beneficial role in promoting clearance of pathogenic fungi and bacteria, and a pathogenic role in autoimmune diseases. Here we identify the tyrosine phosphatas...

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Autors principals: Mauldin, Ileana S., Tung, Kenneth S., Lorenz, Ulrike M.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362360/
https://ncbi.nlm.nih.gov/pubmed/22438258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-09-377069
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