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The protein tyrosine phosphatase SHP-1 modulates the suppressive activity of regulatory T cells

The importance of regulatory T cells (Treg) for immune tolerance is well recognized, yet the signaling molecules influencing their suppressive activity are relatively poorly understood. Here, through in vivo studies and complementary ex vivo studies, we make several important observations. First, we...

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Detalhes bibliográficos
Main Authors: Iype, Tessy, Sankarshanan, Mohan, Mauldin, Ileana S., Mullins, David W., Lorenz, Ulrike
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2974050/
https://ncbi.nlm.nih.gov/pubmed/20952680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000622
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