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The protein tyrosine phosphatase SHP-1 modulates the suppressive activity of regulatory T cells

The importance of regulatory T cells (Treg) for immune tolerance is well recognized, yet the signaling molecules influencing their suppressive activity are relatively poorly understood. Here, through in vivo studies and complementary ex vivo studies, we make several important observations. First, we...

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Bibliografiske detaljer
Main Authors: Iype, Tessy, Sankarshanan, Mohan, Mauldin, Ileana S., Mullins, David W., Lorenz, Ulrike
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2974050/
https://ncbi.nlm.nih.gov/pubmed/20952680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000622
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