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Facilitated aggregation of FG nucleoporins under molecular crowding conditions

Intrinsically disordered and phenylalanine–glycine-rich nucleoporins (FG Nups) form a crowded and selective transport conduit inside the NPC that can only be transited with the help of nuclear transport receptors (NTRs). It has been shown in vitro that FG Nups can assemble into two distinct appearan...

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Autors principals: Milles, Sigrid, Huy Bui, Khanh, Koehler, Christine, Eltsov, Mikhail, Beck, Martin, Lemke, Edward A
Format: Artigo
Idioma:Inglês
Publicat: European Molecular Biology Organization 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596131/
https://ncbi.nlm.nih.gov/pubmed/23238392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2012.204
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