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Facilitated aggregation of FG nucleoporins under molecular crowding conditions

Intrinsically disordered and phenylalanine–glycine-rich nucleoporins (FG Nups) form a crowded and selective transport conduit inside the NPC that can only be transited with the help of nuclear transport receptors (NTRs). It has been shown in vitro that FG Nups can assemble into two distinct appearan...

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Bibliografiske detaljer
Main Authors: Milles, Sigrid, Huy Bui, Khanh, Koehler, Christine, Eltsov, Mikhail, Beck, Martin, Lemke, Edward A
Format: Artigo
Sprog:Inglês
Udgivet: European Molecular Biology Organization 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596131/
https://ncbi.nlm.nih.gov/pubmed/23238392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2012.204
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