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Floppy but not sloppy: Interaction mechanism of FG-nucleoporins and nuclear transport receptors

The nuclear pore complex (NPC) forms a permeability barrier between the nucleus and the cytoplasm. Molecules that are able to cross this permeability barrier encounter different disordered phenylalanine glycine rich nucleoporins (FG-Nups) that act as a molecular filter and regulate the selective NPC...

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Detalhes bibliográficos
Publicado no:Semin Cell Dev Biol
Main Authors: Aramburu, Iker Valle, Lemke, Edward A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611744/
https://ncbi.nlm.nih.gov/pubmed/28669824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2017.06.026
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