ロード中...

Mass Spectrometry Method to Identify Aging Pathways of Sp- and Rp-Tabun Adducts on Human Butyrylcholinesterase Based on the Acid Labile P-N Bond

The phosphoramidate nerve agent tabun inhibits butyrylcholinesterase (BChE) and acetylcholinesterase by making a covalent bond on the active site serine. The adduct loses an alkyl group in a process called aging. The mechanism of aging of the tabun adduct is controversial. Some studies claim that ag...

詳細記述

保存先:
書誌詳細
主要な著者: Jiang, Wei, Cashman, John R., Nachon, Florian, Masson, Patrick, Schopfer, Lawrence M., Lockridge, Oksana
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3595524/
https://ncbi.nlm.nih.gov/pubmed/23345579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kft011
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!