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Nerve agent analogs that produce authentic soman, sarin, tabun, and cyclohexyl methylphosphonate-modified human butyrylcholinesterase

The goal was to test 14 nerve agent model compounds of soman, sarin, tabun, and cyclohexyl methylphosphonofluoridate (GF) for their suitability as substitutes for true nerve agents. We wanted to know whether the model compounds would form the identical covalent adduct with human butyrylcholinesteras...

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Autori principali: Gilley, Cynthia, MacDonald, Mary, Nachon, Florian, Schopfer, Lawrence M., Zhang, Jun, Cashman, John R., Lockridge, Oksana
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2763963/
https://ncbi.nlm.nih.gov/pubmed/19715348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx900090m
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