Application of Palladium-Mediated (18)F-Fluorination to PET Radiotracer Development: Overcoming Hurdles to Translation

New chemistry methods for the synthesis of radiolabeled small molecules have the potential to impact clinical positron emission tomography (PET) imaging, if they can be successfully translated. However, progression of modern reactions from the stage of synthetic chemistry development to the preparat...

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Bibliografiske detaljer
Main Authors: Kamlet, Adam S., Neumann, Constanze N., Lee, Eunsung, Carlin, Stephen M., Moseley, Christian K., Stephenson, Nickeisha, Hooker, Jacob M., Ritter, Tobias
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3595243/
https://ncbi.nlm.nih.gov/pubmed/23554994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059187
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