Application of Palladium-Mediated (18)F-Fluorination to PET Radiotracer Development: Overcoming Hurdles to Translation

New chemistry methods for the synthesis of radiolabeled small molecules have the potential to impact clinical positron emission tomography (PET) imaging, if they can be successfully translated. However, progression of modern reactions from the stage of synthetic chemistry development to the preparat...

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Main Authors: Kamlet, Adam S., Neumann, Constanze N., Lee, Eunsung, Carlin, Stephen M., Moseley, Christian K., Stephenson, Nickeisha, Hooker, Jacob M., Ritter, Tobias
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2013
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3595243/
https://ncbi.nlm.nih.gov/pubmed/23554994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059187
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