Application of Palladium-Mediated (18)F-Fluorination to PET Radiotracer Development: Overcoming Hurdles to Translation

New chemistry methods for the synthesis of radiolabeled small molecules have the potential to impact clinical positron emission tomography (PET) imaging, if they can be successfully translated. However, progression of modern reactions from the stage of synthetic chemistry development to the preparat...

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Detalhes bibliográficos
Main Authors: Kamlet, Adam S., Neumann, Constanze N., Lee, Eunsung, Carlin, Stephen M., Moseley, Christian K., Stephenson, Nickeisha, Hooker, Jacob M., Ritter, Tobias
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3595243/
https://ncbi.nlm.nih.gov/pubmed/23554994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059187
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