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Concerted nucleophilic aromatic substitution with (19)F(−) and (18)F(−)
Nucleophilic aromatic substitution (S(N)Ar) is widely used by organic chemists to functionalize aromatic molecules, and it is the most commonly used method to generate arenes that contain a (18)F for use in PET imaging.(1) A wide range of nucleophiles exhibit S(N)Ar reactivity, and the operational s...
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| Udgivet i: | Nature |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4911285/ https://ncbi.nlm.nih.gov/pubmed/27281221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature17667 |
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