Expression of N-Acetylgalactosamine 4-Sulfate 6-O-Sulfotransferase Involved in Chondroitin Sulfate Synthesis Is Responsible for Pulmonary Metastasis

Chondroitin sulfate (CS) containing E-disaccharide units, glucuronic acid-N-acetylgalactosamine(4, 6-O-disulfate), at surfaces of tumor cells plays a key role in tumor metastasis. However, the molecular mechanism of the metastasis involving the CS chain-containing E-units is not fully understood. In...

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Hlavní autoři: Mizumoto, Shuji, Watanabe, Moto, Yamada, Shuhei, Sugahara, Kazuyuki
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2013
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3595098/
https://ncbi.nlm.nih.gov/pubmed/23555092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/656319
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