A Triple-Transgenic Immunotolerant Mouse Model

Avoiding unwanted immunogenicity is of key importance in the development of therapeutic drug proteins. Animal models are of less predictive value because most of the drug proteins are recognized as foreign proteins. However, different methods have been developed to obtain immunotolerant animal model...

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Detaylı Bibliyografya
Asıl Yazarlar: Brenden, Nina, Madeyski-Bengtson, Katja, Martinsson, Klara, Svärd, Rebecka, Albery-Larsdotter, Sara, Granath, Britta, Lundgren, Hanna, Lövgren, Ann
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Wiley Subscription Services, Inc., A Wiley Company 2013
Konular:
Pharmacokinetics, Pharmacodynamics and Drug Transport and Metabolism
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594975/
https://ncbi.nlm.nih.gov/pubmed/23316010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.23447
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