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A Triple-Transgenic Immunotolerant Mouse Model

Avoiding unwanted immunogenicity is of key importance in the development of therapeutic drug proteins. Animal models are of less predictive value because most of the drug proteins are recognized as foreign proteins. However, different methods have been developed to obtain immunotolerant animal model...

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Detalhes bibliográficos
Main Authors: Brenden, Nina, Madeyski-Bengtson, Katja, Martinsson, Klara, Svärd, Rebecka, Albery-Larsdotter, Sara, Granath, Britta, Lundgren, Hanna, Lövgren, Ann
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594975/
https://ncbi.nlm.nih.gov/pubmed/23316010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.23447
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