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A Triple-Transgenic Immunotolerant Mouse Model

Avoiding unwanted immunogenicity is of key importance in the development of therapeutic drug proteins. Animal models are of less predictive value because most of the drug proteins are recognized as foreign proteins. However, different methods have been developed to obtain immunotolerant animal model...

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Main Authors: Brenden, Nina, Madeyski-Bengtson, Katja, Martinsson, Klara, Svärd, Rebecka, Albery-Larsdotter, Sara, Granath, Britta, Lundgren, Hanna, Lövgren, Ann
格式: Artigo
語言:Inglês
出版: Wiley Subscription Services, Inc., A Wiley Company 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594975/
https://ncbi.nlm.nih.gov/pubmed/23316010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.23447
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