Inhibition of NF-κB by Dehydroxymethylepoxyquinomicin Suppresses Invasion and Synergistically Potentiates Temozolomide and γ-Radiation Cytotoxicity in Glioblastoma Cells

Despite advances in neurosurgery and aggressive treatment with temozolomide (TMZ) and radiation, the overall survival of patients with glioblastoma (GBM) remains poor. Vast evidence has indicated that the nuclear factor NF-κB is constitutively activated in cancer cells, playing key roles in growth a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Brassesco, M. S., Roberto, G. M., Morales, A. G., Oliveira, J. C., Delsin, L. E. A., Pezuk, J. A., Valera, E. T., Carlotti, C. G., Rego, E. M., de Oliveira, H. F., Scrideli, C. A., Umezawa, K., Tone, L. G.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Hindawi Publishing Corporation 2013
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594939/
https://ncbi.nlm.nih.gov/pubmed/23533755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/593020
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