Inhibition of NF-κB by Dehydroxymethylepoxyquinomicin Suppresses Invasion and Synergistically Potentiates Temozolomide and γ-Radiation Cytotoxicity in Glioblastoma Cells

Despite advances in neurosurgery and aggressive treatment with temozolomide (TMZ) and radiation, the overall survival of patients with glioblastoma (GBM) remains poor. Vast evidence has indicated that the nuclear factor NF-κB is constitutively activated in cancer cells, playing key roles in growth a...

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Bibliographic Details
Main Authors: Brassesco, M. S., Roberto, G. M., Morales, A. G., Oliveira, J. C., Delsin, L. E. A., Pezuk, J. A., Valera, E. T., Carlotti, C. G., Rego, E. M., de Oliveira, H. F., Scrideli, C. A., Umezawa, K., Tone, L. G.
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594939/
https://ncbi.nlm.nih.gov/pubmed/23533755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/593020
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