SH1 domain autophosphorylation of P210 BCR/ABL is required for transformation but not growth factor independence.
P210 BCR/ABL is a chimeric oncogene implicated in the pathogenesis of chronic myelogenous leukemia. BCR sequences have been shown to be required for activation of the tyrosine kinase and transforming functions of BCR/ABL. In this work, we show that two other structural requirements for full transfor...
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| Yayımlandı: | Mol Cell Biol |
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| Asıl Yazarlar: | , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Taylor & Francis
1993
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359485/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8441409/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.3.1728-1736.1993 |
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