SH2 domains exhibit high-affinity binding to tyrosine-phosphorylated peptides yet also exhibit rapid dissociation and exchange.

src homology 2 (SH2) domains of intracellular signaling molecules such as phospholipase C-gamma and phosphatidylinositol 3'-kinase-associated protein p85 represent recognition motifs for specific phosphotyrosine-containing regions on activated growth factor receptors. The binding of SH2 domains to a...

Description complète

Détails bibliographiques

Publié dans:	Mol Cell Biol
Auteurs principaux:	Felder, S, Zhou, M, Hu, P, Ureña, J, Ullrich, A, Chaudhuri, M, White, M, Shoelson, S E, Schlessinger, J
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 1993
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359455/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7680095/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.3.1449-1455.1993
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!