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Paxillin α and Crk-associated substrate exert opposing effects on cell migration and contact inhibition of growth through tyrosine phosphorylation

Protein tyrosine phosphorylation accompanies and is essential for integrin signaling. We have shown that tyrosine phosphorylation of paxillin α and Crk-associated substrate (p130(Cas)) is a prominent event on integrin activation in normal murine mammary gland epithelial cells. Tyrosine phosphorylati...

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Detalhes bibliográficos
Main Authors: Yano, Hajime, Uchida, Hiroshi, Iwasaki, Teruo, Mukai, Mutsuko, Akedo, Hitoshi, Nakamura, Kuniaki, Hashimoto, Shigeru, Sabe, Hisataka
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC16824/
https://ncbi.nlm.nih.gov/pubmed/10922062
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