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Paxillin α and Crk-associated substrate exert opposing effects on cell migration and contact inhibition of growth through tyrosine phosphorylation

Protein tyrosine phosphorylation accompanies and is essential for integrin signaling. We have shown that tyrosine phosphorylation of paxillin α and Crk-associated substrate (p130(Cas)) is a prominent event on integrin activation in normal murine mammary gland epithelial cells. Tyrosine phosphorylati...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Yano, Hajime, Uchida, Hiroshi, Iwasaki, Teruo, Mukai, Mutsuko, Akedo, Hitoshi, Nakamura, Kuniaki, Hashimoto, Shigeru, Sabe, Hisataka
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2000
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16824/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10922062/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.16.9076
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