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Manganese Efflux in Parkinsonism: Insights from Newly Characterized SLC30A10 Mutations

Although manganese (Mn) is required for normal cellular function, overexposure to this metal may cause an extrapyramidal syndrome resembling Parkinson’s disease (PD). Notably, high whole-blood Mn levels have been reported in patients with idiopathic PD. Because Mn is both essential at low dose and t...

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Detalhes bibliográficos
Main Authors: DeWitt, Margaret R., Chen, Pan, Aschner, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594538/
https://ncbi.nlm.nih.gov/pubmed/23357421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2013.01.058
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