Prospective analysis of body mass index, physical activity and colorectal cancer risk associated with β-catenin (CTNNB1) status

Dysregulation of the WNT/β-catenin (CTNNB1) signaling pathway is implicated in colorectal carcinoma and metabolic diseases. Considering these roles and cancer prevention, we hypothesized that tumor CTNNB1 status might influence cellular sensitivity to obesity and physical activity. In clinical follo...

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Bibliografiske detaljer
Main Authors: Morikawa, Teppei, Kuchiba, Aya, Lochhead, Paul, Nishihara, Reiko, Yamauchi, Mai, Imamura, Yu, Liao, Xiaoyun, Qian, Zhi Rong, Ng, Kimmie, Chan, Andrew T., Meyerhardt, Jeffrey A., Giovannucci, Edward, Fuchs, Charles S., Ogino, Shuji
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594537/
https://ncbi.nlm.nih.gov/pubmed/23442321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-2276
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